Aseptic Meningitis after BNT-162b2 COVID-19 Vaccination: Case Report and Literature Review [Published online Keio J Med, 72, 102-105, by J-STAGE]

[Published online The Keio Journal of Medicine Vol.72, 102-105, by J-STAGE]
<Title:> Aseptic Meningitis after BNT-162b2 COVID-19 Vaccination: Case Report and Literature Review
<Author(s):> Yuji Kato, Takashi Osada, Nobuo Araki, Shinichi Takahashi
<Corresponding author E-Mill:> yujik(at)saitama-med.ac.jp
<Abstract:> We encountered a-27-year-old female patient who developed refractory severe headache and photophobia after the first dose of COVID-19 vaccine. Despite her prior history of migraine, we diagnosed COVID-19 vaccine-induced aseptic meningitis. Symptoms were significantly resolved after methylprednisolone therapy. On reviewing the literature, we could find only nine similar cases, with over half of them affecting women aged 20 40 years. Although uncommon, aseptic meningitis should be suspected in patients with persistent or delayed onset of headache following COVID-19 vaccination.
<Keywords:> covid-19 vaccine, adverse reaction, aseptic meningitis, steroid
<URL:> https://www.jstage.jst.go.jp/article/kjm/72/4/72_2022-0034-CR/_html