Selected Topics Relating to Functional MRI Study of the Brain [Published online Keio J Med, 68, 73-86, by J-STAGE]

[Published online The Keio Journal of Medicine Vol.68, 73-86, by J-STAGE]
<Title:> Selected Topics Relating to Functional MRI Study of the Brain
<Author(s):> Seiji Ogawa, Yul-Wan Sung
<Corresponding author E-Mill:> ogawa-s(at)
<Abstract:> The authors selected some interesting current topics among many in the field of functional MRI (fMRI) of the brain. The selection was based on authours’ immediate interests in exploring these aspects further; the topics are presented and discussed along with their perspectives. If progress can be made in these areas, it would be very advantageous to the field of brain research. The topics are (I) Detectable MRI signals in response to functional activity of the brain, including the current status of neurocurrent MRI; (II) Vascular-dependent and vascular-independent MRI signals, leading to the distinction of functional and structural MRI; (III) Functional specificity and functional connectivity of local sites, including differences between task-fMRI and resting state fMRI; (IV) Functional networks: an example of application to assessing the vocational aptitude test by fMRI; (V) Neural oscillation relevant to the formation of fMRI signals and of networks; (VI) Upgrading fMRI to “information-content-reflecting” fMRI, discussed as one of the prospects of near-future fMRI.
<Keywords:> fMRI, neurocurrent, resting sate fMRI, functional network, information content

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